According to the White House, first lady Jill Biden has tested positive for coronavirus and will isolate the virus and start a course of antiviral therapy.
The First Lady started experiencing cold-like symptoms late in the evening on Monday after testing negative for COVID-19 on Monday during her normal testing routine.
Jill Biden, 71, is "double-vaccinated, twice boosted, and only suffering moderate symptoms," according to her spokeswoman Elizabeth Alexander.
As per the Centers for Disease Control and Prevention, the first lady would separate from others for at least five days while taking the antiviral medication Paxlovid.
After receiving two consecutively negative COVID tests, she will leave the private residence in South Carolina where she is now residing and return to her home.
President Biden, 79, tested positive for the coronavirus on July 21. The first lady's positive test came a few weeks later.
According to White House press secretary Karine Jean-Pierre, the president's antigen test for the coronavirus came back negative on Tuesday morning.
Nine days after her husband, terminated his isolation due to a COVID-19 re-infection following recovery from a rebound case, she received a positive test result.
A PCR test revealed a positive result for the first lady after she initially tested negative on a quick test.
Occasionally, patients taking the antiviral drug Paxlovid will develop a COVID-19 rebound case, it is known from the doctors.
While on vacation with the president's family, the first lady has been residing in a "private house" on Kiawah Island in South Carolina.